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 Tohoku University Tohoku Medical Megabank Organization (Kazuki Kumada)2024.05.28 1.   Shiraishi Kouya, Takahashi Atsushi, Momozawa Yukihide, et al. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses. Cancer Communications. 2024; 44 (2): 287-293. doi:10.1002/cac2.12498   2.   Yamada Mitsuhiro, Takase Masato, Nakaya Kumi, et al. Fractional exhaled nitric oxide distribution and its relevant factors in the general adult population and its healthy subpopulation. Journal of Allergy and Clinical Immunology: Global. 2024; 3 (3): 100253. doi:10.1016/j.jacig.2024.100253   3.   Hozawa Atsushi, Nakaya Kumi, Nakaya Naoki, et al. Progress report of the Tohoku Medical Megabank Community-Based Cohort Study: Study profile of the repeated center-based survey during second period in Miyagi Prefecture. Journal of Epidemiology. 2024; : JE20230241. doi:10.2188/jea.JE20230241   4.   Harada Sei, Iida Miho, Miyagawa Naoko, et al. Study Profile of the Tsuruoka Metabolomics Cohort Study (TMCS). Journal of Epidemiology. 2024; : JE20230192. doi:10.2188/jea.JE20230192   5.   Aoki Yu-ichi, Taguchi Keiko, Anzawa Hayato, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. The Journal of Biochemistry. 2024; : . doi:10.1093/jb/mvae008   6.   Kudo Hisaaki, Ishida Noriko, Nobukuni Takahiro, et al. Detection and Correction of Sample Misidentifications in a Biobank Using the MassARRAY System and Genomic Information. Biopreservation and Biobanking. 2023; : . doi:10.1089/bio.2022.0211   7.   Taira Makiko, Mugikura Shunji, Mori Naoko, et al. Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study: Rationale, Design, and Background. JMA Journal. 2023; 6 (3): 246-264. doi:10.31662/jmaj.2022-0220   8.   Shiga Hisashi, Takahashi Takahiro, Shiraki Manabu, et al. Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents. Scandinavian Journal of Gastroenterology. 2023; 58 (4): 360-367. doi:10.1080/00365521.2022.2132831   9.   Shindo Norihisa, Kumada Kazuki, Iemura Kenji, et al. Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1. Cell Reports. 2022; 41 (9): 111723. doi:10.1016/j.celrep.2022.111723   10.   Otsuki Akihito, Okamura Yasunobu, Ishida Noriko, et al. Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology. Communications Biology. 2022; 5 (1): 991. doi:10.1038/s42003-022-03953-1   11.   Tayama Hodaka, Karasawa Hideaki, Yamamura Akihiro, et al. The association between ERK inhibitor sensitivity and molecular characteristics in colorectal cancer. Biochemical and Biophysical Research Communications. 2021; 560 : 59-65. doi:10.1016/j.bbrc.2021.04.130   12.   Ogishima Soichi, Nagaie Satoshi, Mizuno Satoshi, et al. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Human Genome Variation. 2021; 8 (1): 44. doi:10.1038/s41439-021-00175-5   13.   Otsuki Akihito, Okamura Yasunobu, Aoki Yuichi, et al. Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis. Molecular and Cellular Biology. 2021; 41 (2): 1-18. doi:10.1128/MCB.00472-20   14.   Tokunaga Hideki, Iida Keita, Hozawa Atsushi, et al. Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2). PLOS ONE. 2021; 16 (1): e0236907. doi:10.1371/journal.pone.0236907   15.   Sakurai-Yageta Mika, Kumada Kazuki, Gocho Chinatsu, et al. Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs. The Journal of Biochemistry. 2021; 170 (3): 399-410. doi:10.1093/jb/mvab060   16.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer. Toxins. 2021; 13 (7): 461. doi:10.3390/toxins13070461   17.   Ishida Noriko, Aoki Yuichi, Katsuoka Fumiki, et al. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. Free Radical Biology and Medicine. 2020; 161 : 71-83. doi:10.1016/j.freeradbiomed.2020.09.023   18.   Shirota Matsuyuki, Saigusa Daisuke, Yamashita Riu, et al. Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy. Medical Mass Spectrometry. 2020; 4 (1): 36-49. doi:10.24508/mms.2020.06.001   19.   Nishizawa Ayako, Kumada Kazuki, Tateno Keiko, et al. Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia. Scientific Reports. 2020; 10 (1): 20027. doi:10.1038/s41598-020-77081-3   20.   Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7   21.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096   22.   Minegishi Naoko, Nishijima Ichiko, Nobukuni Takahiro, et al. Biobank Establishment and Sample Management in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2019; 248 (1): 45-55. doi:10.1620/tjem.248.45   23.   Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0   24.   Kumada Kazuki, Yasuda Jun. Evolutionary acquired robustness and vulnerability in cancer genome: negligible negative selection in carcinogenesis. Translational Cancer Research. 2018; 7 (S4): S445-S448. doi:10.21037/tcr.2018.02.15  

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